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Article

Attenuation and immunogenicity of a live high pathogenic PRRSV vaccine candidate with a 32-amino acid deletion in the nsp2 protein.

Journal of immunology research - 1 Jan 2014

Lu Wenhui, Sun Baoli, Mo Jianyue, Zeng Xiduo, Zhang Guanqun, Wang Lianxiang, Zhou Qingfeng, Zhu Ling, Li Zhili, Xie Qingmei, Bi Yinzuo, Ma Jingyun

Abstract excerpt

A porcine reproductive and respiratory syndrome virus (PRRSV) QY1 was serially passed on Marc-145 cells. Virulence of different intermediate derivatives of QY1 (P5, P60, P80, and P100) were determined. The study found that QY1 had been gradually attenuated during the in vitro process. Pathogenici...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25009824
DOI: 10.1155/2014/810523
PMCID: PMC4070328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25009824-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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