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Developmental Cell Fate and Virulence Are Linked to Trehalose Homeostasis in Cryptococcus neoformans

8 Jul 2014

Abstract excerpt

Among pathogenic environmental fungi, spores are thought to be infectious particles that germinate in the host to cause disease. The meningoencephalitis-causing yeast Cryptococcus neoformans is found ubiquitously in the environment and sporulates in response to nutrient limitation. While the yeast form has been studied extensively, relatively little is known about spore biogenesis, and spore germination has never...

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PMID: 25001408
DOI: 10.1128/ec.00152-14

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