Article
Comprehensive multiplexed protein quantitation delineates eosinophilic and neutrophilic experimental asthma.
BMC pulmonary medicine - 4 Jul 2014
Bergquist Maria, Jonasson Sofia, Hjoberg Josephine, Hedenstierna Göran, Hanrieder Jörg
Abstract excerpt
BACKGROUND: Improvements in asthma diagnosis and management require deeper understanding of the heterogeneity of the complex airway inflammation. We hypothesise that differences in the two major inflammatory phenotypes of asthma; eosinophilic and neutrophilic asthma, will be reflected in the lung protein expression profile of murine asthma models and can be delineated using proteomics of bronchoalveolar lavage...
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