Clinical, molecular and microbial characterisation of the eosinophilic endotype of bronchiectasis: data from the EMBARC-BRIDGE study.

doi:10.1136/thorax-2025-223305

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Clinical, molecular and microbial characterisation of the eosinophilic endotype of bronchiectasis: data from the EMBARC-BRIDGE study.

Thorax - 15 Jun 2026

Pollock Jennifer, Huang Jeffrey T J, Shuttleworth Morven, Long Merete B, Richardson Hollian, Alferes de Lima Daniela, Kuzmanova Elena, Clarke Clare, Shteinberg Michal, Aliberti Stefano, Haworth Charles, Chotirmall Sanjay Haresh, Polverino Eva, Goeminne Pieter C, Loebinger Michael, Lorent Natalie, Ringshausen Felix C, Sibila Oriol, Rodriguez-Suarez Eva, McCrae Christopher, Shoemark Amelia, Chalmers James D

Abstract excerpt

OBJECTIVES: Eosinophilic bronchiectasis is defined by a blood eosinophil count (BEC) ≥300 cells/µL, but blood eosinophils imperfectly reflect airway eosinophilic inflammation. Here, we investigated the relationship between eosinophilic airway inflammation, blood eosinophils and clinical severity in bronchiectasis and explored the phenotype associated with eosinophilic bronchiectasis. METHODS: Sputum from 180...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchiectasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Eosinophilia

Share to Eosinophils

Share to Leukocyte Count

Share to Pseudomonas aeruginosa

Share to Severity of Illness Index

Share to Sputum

Share to Tandem Mass Spectrometry

Source

Open in PubMed

Identifiers

PMID: 41690778
DOI: 10.1136/thorax-2025-223305

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical, molecular and microbial characterisation of the eosinophilic endotype of bronchiectasis: data from the EMBARC-BRIDGE study.PMID 41690778Read ↗

Biomarkers in bronchiectasis.Semantic proximity Read ↗

Eosinophilic phenotypes of airway disease.Semantic proximity Read ↗

Chronic obstructive pulmonary disease's eosinophilic phenotype: Clinical characteristics, biomarkers and biotherapy.Semantic proximity Read ↗

Bronchiectasis: Phenotyping a Complex Disease.Semantic proximity Read ↗

Aspergillus spp. in Non-Cystic Fibrosis Bronchiectasis: Clinical Phenotypes, Molecular Endotypes, and Practical Management-A Narrative Review.Semantic proximity Read ↗

Clinical phenotypes in adult patients with bronchiectasis.Semantic proximity Read ↗

Elevated Eosinophil Counts in Acute Exacerbations of Bronchiectasis: Unveiling a Distinct Clinical Phenotype.Semantic proximity Read ↗

Pathophysiology and genomics of bronchiectasis.Semantic proximity Read ↗

Clinical and Radiological Phenotypes and Endotypes.Semantic proximity Read ↗

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity.Semantic proximity Read ↗

Bronchiectasis: a case-based approach to investigation and management.Semantic proximity Read ↗

Eosinophils in chronic obstructive pulmonary disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.