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Article

The role of TGF-β1–miR-21–ROS pathway in bystander responses induced by irradiated non-small-cell lung cancer cells

3 Jul 2014

Abstract excerpt

BACKGROUND: Many studies have indicated an important implication of radiation-induced bystander effects (RIBEs) in cancer radiotherapy, but the detailed signalling remains unclear. METHODS: The roles of tumour growth factor-beta1 (TGF-β1) and miR-21 in medium-mediated RIBEs in H1299 non-small-cell lung cancer cells were investigated using DNA damage, changes in proliferation and levels of reactive oxygen species...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24992582
DOI: 10.1038/bjc.2014.368

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