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Radiation-Induced Bystander Effects in Cultured Human Stem Cells

2 Dec 2010

Abstract excerpt

BACKGROUND: The radiation-induced "bystander effect" (RIBE) was shown to occur in a number of experimental systems both in vitro and in vivo as a result of exposure to ionizing radiation (IR). RIBE manifests itself by intercellular communication from irradiated cells to non-irradiated cells which may cause DNA damage and eventual death in these bystander cells. It is known that human stem cells (hSC) are...

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PMID: 21152027
DOI: 10.1371/journal.pone.0014195

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