Article
Early stages of we/we wal/wal mouse hair morphogenesis: light and fluorescent microscopy of the whole-mount epidermis.
BioMed research international - 1 Jan 2014
Rippa Alexandra, Leonova Olga, Popenko Vladimir, Vasiliev Andrey, Terskikh Vasily, Vorotelyak Ekaterina
Abstract excerpt
In adult skin, hair follicles cyclically self-renew in a manner that recapitulates embryonic hair follicle morphogenesis. The most common pathology of hair in adults is alopecia, which is hair loss to different extent. There are a number of murine models of alopecia including spontaneous mutations. In the present study, we worked with double homozygous we/we wal/wal mice which demonstrate symptoms closely...
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