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Article

Role of [¹⁸F]FDG PET in prediction of KRAS and EGFR mutation status in patients with advanced non-small-cell lung cancer.

European journal of nuclear medicine and molecular imaging - 1 Nov 2014

Caicedo Carlos, Garcia-Velloso Maria Jose, Lozano Maria Dolores, Labiano Tania, Vigil Diaz Carmen, Lopez-Picazo Jose Maria, Gurpide Alfonso, Zulueta Javier J, Zulueta Javier, Richter Echevarria Jose Angel, Perez Gracia Jose Luis

Abstract excerpt

PURPOSE: The tumour molecular profile predicts the activity of epidermal growth factor receptor (EGFR) inhibitors in non-small-cell lung cancer (NSCLC). However, tissue availability and tumour heterogeneity limit its assessment. We evaluated whether [(18)F]FDG PET might help predict KRAS and EFGR mutation status in NSCLC. METHODS: Between January 2005 and October 2011, 340 NSCLC patients were tested for KRAS and...

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Identifiers

PMID: 24990403
DOI: 10.1007/s00259-014-2833-4

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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