Article
Correlation of F-18 fluorodeoxyglucose-positron emission tomography maximal standardized uptake value and EGFR mutations in advanced lung adenocarcinoma.
Medical oncology (Northwood, London, England) - 1 Mar 2010
Huang Chun-Ta, Yen Rouh-Fang, Cheng Mei-Fang, Hsu Ya-Chieh, Wei Pin-Fei, Tsai Yi-Ju, Tsai Meng-Feng, Shih Jin-Yuan, Yang Chih-Hsin, Yang Pan-Chyr
Abstract excerpt
OBJECTIVE: Epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma are involved in the tumorigenesis and regulation of cell metabolism via Akt signaling. F-18 fluorodeoxyglucose-positron emission tomography ([(18)F]FDG PET), a functional imaging modality, can be used to measure tumor cell metabolism. Thus, in this study, we hypothesize that there exist correlations between EGFR mutation status...
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