Article
Relationship of radiometabolic biomarkers to KRAS mutation status and ALK rearrangements in cases of lung adenocarcinoma.
Tumori - 1 Dec 2019
Aras Gulfidan, Kanmaz Zehra Dilek, Tuncay Esin, Çetinkaya Erdoğan, Yentürk Esin, Kocatürk Celalettin, Öz Büge, Çermik Tevfik Fikret, Purisa Sevim
Abstract excerpt
PURPOSE: Rapid diagnosis of genetic mutations is important for targeted therapies such as EGFR tyrosine kinase inhibitors. KRAS mutation and ALK rearrangement are also important in determining treatment. The purpose of our study was to evaluate the diagnostic value of 18F-FDG PET to predict KRAS mutation and ALK rearrangement in order to determine the frequency of these genetic markers in our lung adenocarcinoma...
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