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Article

Zebrafish as a new model for phenotype-based screening of positive inotropic agents.

Chemical biology & drug design - 1 Mar 2015

Tang Chunlei, Xie Desheng, Feng Bainian

Abstract excerpt

The zebrafish-based assay is a widely used animal model system for cardiovascular research. In this study, we investigated the cardiac defects caused by terfenadine and tested the pharmacological response of digoxin to zebrafish with cardiac defects. The study suggested that zebrafish could be a suitable model for phenotype-based screening and evaluation of positive inotropic agents. This phenotype-based heart...

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PMID: 24990095
DOI: 10.1111/cbdd.12389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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