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Zebrafish Models of Cancer Therapy-Induced Cardiovascular Toxicity

22 Jan 2021

Abstract excerpt

PURPOSE OF REVIEW: Both traditional and novel cancer therapies can cause cardiovascular toxicity in patients. In vivo models integrating both cardiovascular and cancer phenotypes allow for the study of on- and off-target mechanisms of toxicity arising from these agents. The zebrafish is the optimal whole organism model to screen for cardiotoxicity in a high throughput manner, while simultaneously assessing the...

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PMID: 33499052
DOI: 10.3390/jcdd8020008

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