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Article

Maladaptive decision making and substance use outcomes in high-risk individuals: preliminary evidence for the role of 5-HTTLPR variation.

Journal of studies on alcohol and drugs - 1 Jul 2014

O'Brien Jessica W, Lichenstein Sarah D, Hill Shirley Y

Abstract excerpt

OBJECTIVE: Individuals with multiple alcohol-dependent (AD) relatives are at increased risk for substance use disorders (SUDs). Prospective, longitudinal studies of high-risk (HR) individuals afford the opportunity to determine potential risk markers of SUDs. The current study assessed the effect of familial risk and genetic variation on Iowa Gambling Task (IGT) performance and tested for an association between...

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Identifiers

PMID: 24988263
DOI: 10.15288/jsad.2014.75.643
PMCID: PMC4108605

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