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Autophagy: Mechanisms and Therapeutic Potential of Flavonoids in Cancer

21 Jan 2021

Abstract excerpt

Autophagy, which is a conserved biological process and essential mechanism in maintaining homeostasis and metabolic balance, enables cells to degrade cytoplasmic constituents through lysosomes, recycle nutrients, and survive during starvation. Autophagy exerts an anticarcinogenic role in normal cells and inhibits the malignant transformation of cells. On the other hand, aberrations in autophagy are involved in...

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PMID: 33494431
DOI: 10.3390/biom11020135

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