Article
An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine.
Oncotarget - 30 Jul 2014
Maldonado Leonel, Brait Mariana, Michailidi Christina, Munari Enrico, Driscoll Tina, Schultz Luciana, Bivalacqua Trinity, Schoenberg Mark, Sidransky David, Netto George J, Hoque Mohammad Obaidul
Abstract excerpt
By a candidate gene approach, we analyzed the promoter methylation (PM) of 8 genes genes (ARF, TIMP3, RAR-β2, NID2, CCNA1, AIM1, CALCA and CCND2) by quantitative methylation specific PCR (QMSP) in DNA of 17 non-recurrent and 19 recurrent noninvasive low grade papillary urothelial cell carcinoma (LGPUCC) archival tissues. Among the genes tested, by establishing an empiric cutoff value, CCND2, CCNA1, NID2, and...
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