Article
Molecular epidemiology of hepatitis B virus genotypes circulating in acute hepatitis B patients in the Campania region.
Journal of medical virology - 1 Oct 2014
Sagnelli Caterina, Ciccozzi Massimo, Pisaturo Mariantonietta, Zehender Gianguglielmo, Lo Presti Alessandra, Alessio Loredana, Starace Mario, Lovero Domenica, Sagnelli Evangelista, Coppola Nicola
Abstract excerpt
Fifty-three HBV-DNA-positive patients with symptomatic acute hepatitis B were enrolled from 1999 to 2010 to evaluate molecular and phylogenetic changes in HBV in southern Italy. HBV polymerase region was evaluated by direct sequencing in plasma samples obtained at first observation. Different data sets were aligned and a phylogenetic tree was inferred using PhyML program. Statistical robustness was confirmed with...
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