The unexpected high prevalence of HBV subgenotype D4 in patients with chronic hepatitis B in Galicia, a northwestern Spanish region, reflects strong links with Latin America.

doi:10.1016/j.jcv.2022.105195

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Article

The unexpected high prevalence of HBV subgenotype D4 in patients with chronic hepatitis B in Galicia, a northwestern Spanish region, reflects strong links with Latin America.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2022

Trastoy Rocío, Gonzalez-Alba José María, Soriano Vicente, Rodriguez-Calviño José Javier, de Mendoza Carmen, Costa José Javier, Cea María, Barbeito Gema, Corral Octavio, Gómez-Gallego Félix, Pérez Del Molino María Luisa, Carlos Galán Juan, Aguilera Antonio

Abstract excerpt

BACKGROUND: Hepatitis B virus (HBV) comprises 9 genotypes and multiple subgenotypes that depict differences in geographic distribution, clinical outcome and response to antiviral therapy. However, the molecular epidemiology of HBV geno/subgenotypes is globally scarce. In Spain, HBV genotype D seems to be more prevalent in the northwestern regions compared to the rest of the country for unclear reasons. METHODS:...

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PMID: 35661583
DOI: 10.1016/j.jcv.2022.105195

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