Article
Placental sprouty 2 (SPRY2): relation to placental growth and maternal metabolic status.
Neonatology - 1 Jan 2014
Bassols Judit, Moreno-Navarrete Jose, Carreras-Badosa Gemma, Diaz Marta, Prats-Puig Anna, Palomer Anna-Maria, de Zegher Francis, Ibáñez Lourdes, Fernandez-Real Jose-Manuel, Lopez-Bermejo Abel
Abstract excerpt
BACKGROUND: SPROUTY2 (SPRY2) is a membrane-associated protein expressed by placental macrophages with regulatory roles in tissue growth and development. The SPRY2 locus was shown to be associated with body fat distribution and susceptibility to type 2 diabetes. OBJECTIVES: We assessed whether SPRY2 mRNA levels are related with maternal metabolic status and with placental weight. We also studied the association of...
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