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Circulating Very Small Embryonic-Like Stem Cells in Cardiovascular Disease

16 Dec 2010

Abstract excerpt

Very small embryonic-like cells (VSELs) are a population of stem cells residing in the bone marrow (BM) and several organs, which undergo mobilization into peripheral blood (PB) following acute myocardial infarction and stroke. These cells express markers of pluripotent stem cells (PSCs), such as Oct-4, Nanog, and SSEA-1, as well as early cardiac, endothelial, and neural tissue developmental markers. VSELs can be...

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PMID: 21165781
DOI: 10.1007/s12265-010-9254-y

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