Statistical stage transition detection method for small sample gene expression time series data.

Abstract excerpt

In terms of their internal (genetic) and external (phenotypic) states, living cells are always changing at varying rates. Periods of stable or low rate of change are often called States, Stages, or Phases, whereas high-rate periods are called Transitions or Transients. While states and transitions are observed phenotypically, such as cell differentiation, cancer progression, for example, are related with gene...

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