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Article

Genetic diversity in HIV-1 subtype C LTR from Brazil and Mozambique generates new transcription factor-binding sites.

Viruses - 23 Jun 2014

Boullosa José, Bachu Mahesh, Bila Dulce, Ranga Udaykumar, Süffert Theodoro, Sasazawa Tomoko, Tanuri Amilcar

Abstract excerpt

The HIV-1 subtype C has been substituting the subtype B population in southern Brazil. This phenomenon has been previously described in other countries, suggesting that subtype C may possess greater fitness than other subtypes. The HIV-1 long-terminal repeat (LTR) is an important regulatory region critical for the viral life cycle. Sequence insertions immediately upstream of the viral enhancer are known as the...

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Identifiers

PMID: 24960272
DOI: 10.3390/v6062495
PMCID: PMC4074939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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