Article
Influence of immune responses in gene/stem cell therapies for muscular dystrophies.
BioMed research international - 1 Jan 2014
Farini Andrea, Sitzia Clementina, Erratico Silvia, Meregalli Mirella, Torrente Yvan
Abstract excerpt
Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing the dystrophic muscle damage using gene transfer or cell therapy. Here we discussed current...
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