Article
Effect of VKORC1, CYP2C9 and CYP4F2 genetic variants in early outcomes during acenocoumarol treatment.
Pharmacogenomics - 1 May 2014
Cerezo-Manchado Juan Jose, Roldan Vanessa, Rosafalco Mario, Anton Ana Isabel, Arroyo Ana Belen, Garcia-Barbera Nuria, Martínez Ana Belen, Padilla Jose, Corral Javier, Vicente Vicente, Gonzalez-Conejero Rocio
Abstract excerpt
AIM: To analyze VKORC1, CYP2C9 and CYP4F2 polymorphisms in relation to the main outcomes in the first stages of acenocoumarol therapy. PATIENTS & METHODS: Nine hundred and forty one patients who had started therapy and in whom time to stable dosage, time to over-anticoagulation and adverse events occurred during 3 first months were retrospectively analyzed. RESULTS: VKORC1 AA patients needed fewer days to reach...
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