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Article

Mobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogen.

Cancer letters - 1 Oct 2014

Robinson Kelly M, Dunning Hotopp Julie C

Abstract excerpt

Insertional mutagenesis has been repeatedly demonstrated in cancer genomes and has a role in oncogenesis. Mobile genetic elements can induce cancer development by random insertion into cancer related genes or by inducing translocations. L1s are typically implicated in cancers of an epithelial cell origin, while Alu elements have been implicated in leukemia as well as epithelial cell cancers. Likewise, viral...

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Share to Bacterial Infections
Share to Cell Transformation, Viral
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Interspersed Repetitive Sequences

Share to Mutagenesis, Insertional

Share to Tumor Virus Infections

Share to Virus Integration

Source

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Identifiers

PMID: 24956175
DOI: 10.1016/j.canlet.2014.05.021
PMCID: PMC4134975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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