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Article

Molecular evolution of a novel family of putative calcium transporters.

PloS one - 1 Jan 2014

Demaegd Didier, Colinet Anne-Sophie, Deschamps Antoine, Morsomme Pierre

Abstract excerpt

The UPF0016 family is a group of uncharacterized membrane proteins, well conserved through evolution and defined by the presence of one or two copies of an E-Φ-G-D-(KR)-(ST) consensus motif. Our previous results have shown that two members of this family, the human TMEM165 and the budding yeast Gdt1p, are functionally related and might form a new group of cation/Ca2+ exchangers. Most members of the family are...

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Identifiers

PMID: 24955841
DOI: 10.1371/journal.pone.0100851
PMCID: PMC4067407

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Source receipt: pubmed, retrieved 7 Sept 2026.

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