Article
The PLAU P141L single nucleotide polymorphism is associated with collateral circulation in patients with coronary artery disease.
Revista espanola de cardiologia (English ed.) - 1 Jul 2014
Duran Joan, Sánchez-Olavarría Pilar, Mola Marina, Götzens Víctor, Carballo Julio, Martín-Pelegrina Eva, Petit Màrius, García Del Blanco Bruno, García-Dorado David, de Anta Josep M
Abstract excerpt
INTRODUCTION AND OBJECTIVES: Urokinase-type plasminogen activator, which is encoded by the PLAU gene, plays a prominent role during collateral arterial growth. We investigated whether the PLAU P141L (C > T) polymorphism, which causes a mutation in the kringle domain of the protein, is associated with coronary collateral circulation in a cohort of 676 patients with coronary artery disease. METHODS: The...
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