Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Presence of human polyomavirus 6 in mutation-specific BRAF inhibitor-induced epithelial proliferations.

JAMA dermatology - 1 Nov 2014

Schrama David, Groesser Leopold, Ugurel Selma, Hafner Christian, Pastrana Diana V, Buck Christopher B, Cerroni Lorenzo, Theiler Anna, Becker Jürgen C

Abstract excerpt

IMPORTANCE: A frequent adverse effect of mutation-specific BRAF inhibitor therapy is the induction of epithelial proliferations including cutaneous squamous cell carcinomas. To date, the only factor identified contributing to their development is the activation of the mitogen-activated signal transduction cascade by mutations in the RAS genes. However, these mutations explain only 60% of the tumors; hence, it is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Indoles
Share to Papillomaviridae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Papillomavirus Infections

Share to Polyomavirus

Share to Polyomavirus Infections

Share to Sulfonamides

Share to Tumor Virus Infections

Share to Vemurafenib

Source

Open in PubMed Open full text

Identifiers

PMID: 24943872
DOI: 10.1001/jamadermatol.2014.1116
PMCID: PMC8369517

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Presence of human polyomavirus 6 in mutation-specific BRAF inhibitor-induced epithelial proliferations.PMID 24943872Read ↗

Frequent detection of human polyomavirus 6 in keratoacanthomasSemantic proximity Read ↗

Emerging role of human polyomaviruses 6 and 7 in human cancersSemantic proximity Read ↗

Merkel cell polyomavirus and human papilloma virus in proliferative skin lesions arising in patients treated with BRAF inhibitors.Semantic proximity Read ↗

Polyomaviruses of the skin: integrating molecular and clinical advances in an emerging class of virusesSemantic proximity Read ↗

Increased Detection of Merkel Cell Polyomavirus in Non-Melanoma Skin Cancer and Its Association with Host Immunogenetic ProfileSemantic proximity Read ↗

Merkel Cell Polyoma Virus and Cutaneous Human Papillomavirus Types in Skin Cancers: Optimal Detection Assays, Pathogenic Mechanisms, and Therapeutic VaccinationSemantic proximity Read ↗

Detection of human polyomaviruses MCPyV, HPyV6, and HPyV7 in malignant and non‐malignant tonsillar tissuesSemantic proximity Read ↗

Human Polyomaviruses in Skin DiseasesSemantic proximity Read ↗

Are human polyomaviruses co‐factors for cancers induced by other oncoviruses?Semantic proximity Read ↗

The novel human polyomaviruses <scp>HPyV</scp>6, 7, 9 and beyondSemantic proximity Read ↗

Merkel cell polyomavirus infection and persistence modelled in skin organoidsSemantic proximity Read ↗

No human virus sequences detected by next-generation sequencing in benign verrucous skin tumors occurring in BRAF-inhibitor-treated patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.