Article
Genetic variations in RORα are associated with chronic obstructive pulmonary disease.
Journal of human genetics - 1 Aug 2014
Yuan Yiming, Hou Xiaoming, Zhang Jinlong, Chen Yulong, Feng Yulin, Su Zhiguang
Abstract excerpt
Retinoic acid receptor-related orphan receptor-α (RORα) plays a key role in the regulation of lipid and cholesterol metabolism that has been implicated in the development of chronic obstructive pulmonary disease (COPD). The aim of this study was to determine the frequencies of single-nucleotide polymorphisms (SNPs) in RORα gene in a Chinese population and their possible association with COPD susceptibility. Nine...
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