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Mosquito and<i>Drosophila</i>entomobirnaviruses suppress dsRNA- and siRNA-induced RNAi

17 Jun 2014

Abstract excerpt

RNA interference (RNAi) is a crucial antiviral defense mechanism in insects, including the major mosquito species that transmit important human viruses. To counteract the potent antiviral RNAi pathway, insect viruses encode RNAi suppressors. However, whether mosquito-specific viruses suppress RNAi remains unclear. We therefore set out to study RNAi suppression by Culex Y virus (CYV), a mosquito-specific virus of...

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PMID: 24939903
DOI: 10.1093/nar/gku528

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