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Yellow fever virus capsid protein is a potent suppressor of RNA silencing that binds double-stranded RNA

14 Nov 2016

Abstract excerpt

Mosquito-borne flaviviruses, including yellow fever virus (YFV), Zika virus (ZIKV), and West Nile virus (WNV), profoundly affect human health. The successful transmission of these viruses to a human host depends on the pathogen's ability to overcome a potentially sterilizing immune response in the vector mosquito. Similar to other invertebrate animals and plants, the mosquito's RNA silencing pathway comprises its...

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PMID: 27849599
DOI: 10.1073/pnas.1600544113

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