Article
Impacts of the Callipyge mutation on ovine plasma metabolites and muscle fibre type.
PloS one - 1 Jan 2014
Li Juan, Greenwood Paul L, Cockett Noelle E, Hadfield Tracy S, Vuocolo Tony, Byrne Keren, White Jason D, Tellam Ross L, Schirra Horst Joachim
Abstract excerpt
The ovine Callipyge mutation causes postnatal muscle hypertrophy localized to the pelvic limbs and torso, as well as body leanness. The mechanism underpinning enhanced muscle mass is unclear, as is the systemic impact of the mutation. Using muscle fibre typing immunohistochemistry, we confirmed muscle specific effects and demonstrated that affected muscles had greater prevalence and hypertrophy of type 2X fast...
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