Article
Identification of virulence determinants in influenza viruses.
Analytical chemistry - 15 Jul 2014
Negri Pierre, Choi Joo Young, Jones Cheryl, Tompkins S Mark, Tripp Ralph A, Dluhy Richard A
Abstract excerpt
To date there is no rapid method to screen for highly pathogenic avian influenza strains that may be indicators of future pandemics. We report here the first development of an oligonucleotide-based spectroscopic assay to rapidly and sensitively detect a N66S mutation in the gene coding for the PB1-F2 protein associated with increased virulence in highly pathogenic pandemic influenza viruses. 5'-Thiolated ssDNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.