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Common variants of xeroderma pigmentosum genes and prostate cancer risk.

Gene - 10 Aug 2014

Mirecka Aneta, Paszkowska-Szczur Katarzyna, Scott Rodney J, Górski Bohdan, van de Wetering Thierry, Wokołorczyk Dominika, Gromowski Tomasz, Serrano-Fernandez Pablo, Cybulski Cezary, Kashyap Aniruddh, Gupta Satish, Gołąb Adam, Słojewski Marcin, Sikorski Andrzej, Lubiński Jan, Dębniak Tadeusz

Abstract excerpt

The genetic basis of prostate cancer (PC) is complex and appears to involve multiple susceptibility genes. A number of studies have evaluated a possible correlation between several NER gene polymorphisms and PC risk, but most of them evaluated only single SNPs among XP genes and the results remain inconsistent. Out of 94 SNPs located in seven XP genes (XPA-XPG) a total of 15 SNPs were assayed in 720 unselected...

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PMID: 24933002
DOI: 10.1016/j.gene.2014.06.026

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XPA

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