Article
Association of XPC Gene Polymorphisms with Prostate Cancer Risk.
Clinical laboratory - 1 Jan 2016
Kahnamouei Shima A, Narouie Behzad, Sotoudeh Mehdi, Mollakouchekian Mohammad J, Simforoosh Nasser, Ziaee Seyed A M, Samzadeh Mohammad, Afshari Mahdi, Jamaldini Seyed H, Imeni Mahdieh, Hasanzad Mandana
Abstract excerpt
BACKGROUND: Defective DNA repair capacity caused by inherited polymorphisms could be associated with cancer susceptibility. One of the major repair pathways is Nucleotide Excision Repair (NER). We investigated Xeroderma Pigmentosum complementation group C (XPC) polymorphisms (Lys939Gln, PAT) with the risk of prostate cancer. METHODS: 154 confirmed prostate cancer patients and 205 Benign Prostate Hyperplasia (BPH)...
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