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Article

Polarizing intestinal epithelial cells electrically through Ror2.

Journal of cell science - 1 Aug 2014

Cao Lin, McCaig Colin D, Scott Roderick H, Zhao Siwei, Milne Gillian, Clevers Hans, Zhao Min, Pu Jin

Abstract excerpt

The apicobasal polarity of enterocytes determines where the brush border membrane (apical membrane) will form, but how this apical membrane faces the lumen is not well understood. The electrical signal across the epithelium could serve as a coordinating cue, orienting and polarizing enterocytes. Here, we show that applying a physiological electric field to intestinal epithelial cells, to mimic the natural...

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Source

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Identifiers

PMID: 24928904
DOI: 10.1242/jcs.146357
PMCID: PMC4117229

Genes

ALPI
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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