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Kisspeptin Regulation of Genes Involved in Cell Invasion and Angiogenesis in First Trimester Human Trophoblast Cells

12 Jun 2014

Abstract excerpt

The precise regulation of extravillous trophoblast invasion of the uterine wall is a key process in successful pregnancies. Kisspeptin (KP) has been shown to inhibit cancer cell metastasis and placental trophoblast cell migration. In this study primary cultures of first trimester human trophoblast cells have been utilized in order to study the regulation of invasion and angiogenesis-related genes by KP....

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PMID: 24923321
DOI: 10.1371/journal.pone.0099680

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Related research

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Kisspeptin Regulation of Genes Involved in Cell Invasion and Angiogenesis in First Trimester Human Trophoblast CellsPMID 24923321Read ↗

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Aquaporin 3 promotes human extravillous trophoblast migration and invasionSemantic proximity Read ↗

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Leptin-Promoted Human Extravillous Trophoblast Invasion Is MMP14 Dependent and Requires the Cross Talk Between Notch1 and PI3K/Akt Signaling1Semantic proximity Read ↗

Elevated Expression of KiSS-1 in Placenta of Chinese Women with Early-Onset PreeclampsiaSemantic proximity Read ↗

Rac1/β-Catenin Signalling Pathway Contributes to Trophoblast Cell Invasion by Targeting Snail and MMP9Semantic proximity Read ↗

miR-183-5p suppressed the invasion and migration of HTR-8/SVneo trophoblast cells partly via targeting MMP-9 in preeclampsiaSemantic proximity Read ↗

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