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Article

Contribution of DNA double-strand break repair gene XRCC3 genotypes to oral cancer susceptibility in Taiwan.

Anticancer research - 1 Jun 2014

Tsai Chia-Wen, Chang Wen-Shin, Liu Juhn-Cherng, Tsai Ming-Hsui, Lin Cheng-Chieh, Bau Da-Tian

Abstract excerpt

The DNA repair gene X-ray repair cross complementing protein 3 (XRCC3) is thought to play a major role in double-strand break repair and in maintaining genomic stability. Very possibly, defective double-strand break repair of cells can lead to carcinogenesis. Therefore, a case-control study was performed to reveal the contribution of XRCC3 genotypes to individual oral cancer susceptibility. In this hospital-based...

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PMID: 24922659

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XRCC3

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