Article
Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Dec 2014
Guo XueLiang, Pace Rhonda G, Stonebraker Jaclyn R, O'Neal Wanda K, Knowles Michael R
Abstract excerpt
BACKGROUND: Mucins are excellent candidates for contributing to the presence of meconium ileus (MI) in cystic fibrosis (CF) due to their extensive genetic variation and known function in intestinal physiology. The length of variants in mucin central repetitive regions has not been explored as "risk" factors for MI in CF. METHODS: We investigated the length polymorphisms in the central repetitive regions of MUC1,...
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