Article
Screening of SOD1, FUS and TARDBP genes in patients with amyotrophic lateral sclerosis in central-southern China.
Scientific reports - 8 Sept 2016
Hou Lihua, Jiao Bin, Xiao Tingting, Zhou Lu, Zhou Zhifan, Du Juan, Yan Xinxiang, Wang Junling, Tang Beisha, Shen Lu
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons of the brain, brainstem and spinal cord. To date, mutations in more than 30 genes have been linked to the pathogenesis of ALS. Among them, SOD1, FUS and TARDBP are ranked as the three most common genes associated with ALS. However, no mutation analysis has been reported in central-southern China. In this study, we...
Topics
Join the communities discussing this publication.