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Article

The relationship between plasma concentration of metoprolol and CYP2D6 genotype in patients with ischemic heart disease.

Pharmacological reports : PR - 1 Jun 2014

Wojtczak Anna, Wojtczak Maciej, Skrętkowicz Jadwiga

Abstract excerpt

BACKGROUND: Metoprolol is the one of the most commonly used β-blockers in the treatment of ischemic heart disease and it is extensively metabolized in the liver undergoing oxidation by CYP2D6 isoenzyme of cytochrome P450. Gene encoding the CYP2D6 enzyme is characterized by genetic polymorphism. T...

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Source

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PMID: 24905532
DOI: 10.1016/j.pharep.2013.12.010

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24905532-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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