Article
Synaptonemal complex protein 3 is a prognostic marker in cervical cancer.
PloS one - 1 Jan 2014
Cho Hanbyoul, Noh Kyung Hee, Chung Joon-Yong, Takikita Mikiko, Chung Eun Joo, Kim Bo Wook, Hewitt Stephen M, Kim Tae Woo, Kim Jae-Hoon
Abstract excerpt
Synaptonemal complex protein 3 (SCP3), a member of Cor1 family, is up-regulated in various cancer cells; however, its oncogenic potential and clinical significance has not yet been characterized. In the present study, we investigated the oncogenic role of SCP3 and its relationship with phosphorylated AKT (pAKT) in cervical neoplasias. The functional role of SCP3 expression was investigated by overexpression or...
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