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Article

Atg1 kinase organizes autophagosome formation by phosphorylating Atg9

28 Apr 2014

Abstract excerpt

The conserved Ser/Thr kinase Atg1/ULK1 plays a crucial role in the regulation of autophagy. However, only very few Atg1 targets have been identified, impeding elucidation of the mechanisms by which Atg1 regulates autophagy. In our study, we determined the Saccharomyces cerevisiae Atg1 consensus phosphorylation sequence using a peptide array-based approach. Among proteins containing this sequence we identified...

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PMID: 24905091
DOI: 10.4161/auto.28971

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