Article
Collecting duct-derived cells display mesenchymal stem cell properties and retain selective in vitro and in vivo epithelial capacity.
Journal of the American Society of Nephrology : JASN - 1 Jan 2015
Li Joan, Ariunbold Usukhbayar, Suhaimi Norseha, Sunn Nana, Guo Jinjin, McMahon Jill A, McMahon Andrew P, Little Melissa
Abstract excerpt
We previously described a mesenchymal stem cell (MSC)-like population within the adult mouse kidney that displays long-term colony-forming efficiency, clonogenicity, immunosuppression, and panmesodermal potential. Although phenotypically similar to bone marrow (BM)-MSCs, kidney MSC-like cells display a distinct expression profile. FACS sorting from Hoxb7/enhanced green fluorescent protein (GFP) mice identified...
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