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Article

A mutated vitamin D receptor in hereditary vitamin D-resistant rickets prevents induction of bronchial hyperreactivity and inflammation.

The Journal of clinical endocrinology and metabolism - 1 Sept 2014

Bar-Yoseph Ronen, Bentur Lea, Goldbart Aviv, Livnat Galit, Hakim Fahed, Weisman Yosef, Tiosano Dov

Abstract excerpt

CONTEXT: Previous studies have reported an association between vitamin D deficiency and asthma. Hereditary 1,25-dihydroxyvitamin D-resistant rickets (HVDRR) patients provide a natural model to assess the role of the vitamin D receptor (VDR) in regulating human lung immune responses and airway hyperreactivity. OBJECTIVES: The aim of the study was to determine the role of the VDR on lung functions, airways, and...

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Source

Identifiers

PMID: 24885630
DOI: 10.1210/jc.2014-1396

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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