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Vitamin D constrains inflammation by modulating the expression of key genes on Chr17q12-21.1

25 Aug 2023

Abstract excerpt

Vitamin D possesses immunomodulatory functions and vitamin D deficiency has been associated with the rise in chronic inflammatory diseases, including asthma (Litonjua and Weiss, 2007). Vitamin D supplementation studies do not provide insight into the molecular genetic mechanisms of vitamin D-mediated immunoregulation. Here, we provide evidence for vitamin D regulation of two human chromosomal loci, Chr17q12-21.1...

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PMID: 38567749
DOI: 10.7554/elife.89270

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