Article
Exploring the evolutionary route of the acquisition of betaine aldehyde dehydrogenase activity by plant ALDH10 enzymes: implications for the synthesis of the osmoprotectant glycine betaine.
BMC plant biology - 29 May 2014
Muñoz-Clares Rosario A, Riveros-Rosas Héctor, Garza-Ramos Georgina, González-Segura Lilian, Mújica-Jiménez Carlos, Julián-Sánchez Adriana
Abstract excerpt
BACKGROUND: Plant ALDH10 enzymes are aminoaldehyde dehydrogenases (AMADHs) that oxidize different ω-amino or trimethylammonium aldehydes, but only some of them have betaine aldehyde dehydrogenase (BADH) activity and produce the osmoprotectant glycine betaine (GB). The latter enzymes possess alanine or cysteine at position 441 (numbering of the spinach enzyme, SoBADH), while those ALDH10s that cannot oxidize...
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