Article
Predictive factors to targeted treatment in gastrointestinal carcinomas.
Cancer biomarkers : section A of Disease markers - 1 Jan 2014
Silvestris Nicola, Marech Ilaria, Brunetti Anna Elisabetta, Azzariti Amalia, Numico Gianmauro, Cicero Giuseppe, Delcuratolo Sabina, De Luca Raffaele, Burz Claudia, Lorusso Vito
Abstract excerpt
Most cancers are traditionally treated with either chemotherapeutic agents, radiotherapy, or both. Identification of specific molecular characteristics of tumors and the advent of molecular-targeted drugs not only enhance the efficacy but also decrease the toxicity of treatment. These new therapies may target pathways critical to tumor development or specific driver mutations in cancer cells. This understanding...
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