Article
High prevalence of subtype F in newly diagnosed HIV-1 persons in northwest Spain and evidence for impaired treatment response.
AIDS (London, England) - 31 Jul 2014
Pernas Berta, Grandal Marta, Mena Alvaro, Castro-Iglesias Angeles, Cañizares Angelina, Wyles David L, López-Calvo Soledad, Pértega Sonia, Rodríguez-Osorio Iria, Pedreira Jose Domingo, Poveda Eva
Abstract excerpt
HIV-1 non-B subtype variants were found in 37.8% of 296 newly diagnosed persons in northwest Spain over the past 5 years. Subtype F was the most prevalent non-B subtype (29.6%) and displayed preferential transmission among MSM. Virologic response rates to antiretroviral therapy were lower among F subtypes compared to B subtypes at weeks 24 (31% vs. 78.3%), 48 (51.7% vs. 85.2%), and 96 (61.1% vs. 94.3%) of...
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