Article
NKG2D functions as an activating receptor on natural killer cells in the common marmoset (Callithrix jacchus).
International immunology - 1 Nov 2014
Watanabe Masamichi, Kudo Yohei, Kawano Mitsuko, Nakayama Masafumi, Nakamura Kyohei, Kameda Mai, Ebara Masamune, Sato Takeki, Nakamura Marina, Omine Kaito, Kametani Yoshie, Suzuki Ryuji, Ogasawara Kouetsu
Abstract excerpt
The natural killer group 2 membrane D (NKG2D) receptor is an NK-activating receptor that plays an important role in host defense against tumors and viral infections. Although the marmoset is an important and reliable animal model, especially for the study of human-specific viral infections, functional characterization of NKG2D on marmoset NK cells has not previously been conducted. In the present study, we...
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