Article
Pharmacogenetic biomarkers for predicting drug response.
Expert review of molecular diagnostics - 1 Jul 2014
Bank Paul Christiaan, Swen Joachim Jesse, Guchelaar Henk-Jan
Abstract excerpt
Drug response shows significant interpatient variability and evidence that genetics influences outcome of drug therapy has been known for more than five decades. However, the translation of this knowledge to clinical practice remains slow. Using examples from clinical practice six considerations about the implementation of pharmacogenetics (PGx) into routine care are discussed: the need for PGx biomarkers; the...
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